Updated on February 15, 2024

·

Created on July 9, 2016

HemoCue WBC DIFF System

Upcoming Update

The HemoCue WBC DIFF System measures white blood cell in order to rapidly provide information about the state of the immune system to medical professionals.

Developed By
  1. HemoCue
Tested By
  • Hammersmith Hospital
Content Partners
Unknown

Author

Product Description

The HemoCue WBC DIFF System measures white blood cell (WBC) count including a five-part differential at the point of care in order to rapidly provide information about the state of the immune system to medical professionals.

Target SDGs

SDG 3: Good Health and Well-Being

Market Suggested Retail Price

$1,700.00

Target Users (Target Impact Group)

Small and Medium-sized Enterprises, Public Sector Agencies

Distributors / Implementing Organizations

 Distributed by manufacturer

Manufacturing/Building Method

Waiting for response from manufacturer

Intellectural Property Type

Select Type

User Provision Model

A WBC DIFF can be purchased from contacting HemoCue on their website. Additional websites, such as Wilburn Medical, also carry the device.

Distributions to Date Status

Unknown

Consumables

Gloves, alcohol wipe, needle, cuvette

Detection sensitivity

300-30000/µL

Indispensable equipment for function (Y/N)

N

Maintenance or calibration required by user at time of use? (Y/N)

N

Number of Tests Performed

1

Power supply type: Continuous, Recharging only (V, time required, battery life), Other

AC Adapter or 6 C batteries

Time required for procedure (minutes)

5 minutes

Design Specifications

A drop of blood is put into the Hemocue system and within 5 minutes, information about immune cell count is displayed. This video (1) shows a step-by-step use of the product.

Product Schematics

Technical Support

Provided by manufacturer

Replacement Components

Replacement consumables can be purchased from contacting HemoCue on their website. Additional websites, such as Wilburn Medical, also carry the replacement consumables.

Lifecycle

5 - 10 years

Manufacturer Specified Performance Parameters

The manufacturer specifies a detection range of 300-30000 cells/µL, with a sample volume of 10uL, and a measurement time of less than 5 minutes.

Vetted Performance Status

In the independent study by Hammersmith Hospital, the device provided reliable comparability in the range of 0.4–30.0 × 109/l. This is slightly narrower than the range of 0.3–35 × 109/l specified by the manufacturer; however, samples with WBC < 0.4 × 109/l were flagged as low (code LLL) and conversely, those with counts above 30.0 × 109/l were flagged as high (code HHH); thus, in a clinical setting, this flagging would provide adequately reliable information.

Safety

Unreliably measuring immune function could provide incorrect information to doctors, leading to incorrect diagnosis and treatment.

Complementary Technical Systems

None

Academic Research and References

Osei-Bimpong, A., Jury, C., McLean, R., Lewis, S.M. “Point-of-care method for total white cell count: an evaluation of the HemoCue WBC device.” Int. J. Lab Hematol, 31:6 (2009)

Casey, Janet R., and Michael E. Pichichero. 2009. “A Comparison of 2 White Blood Cell Count Devices to Aid Judicious Antibiotic Prescribing.” Clinical Pediatrics 48 (3): 291–94.

Russcher, H., N. Van Deursen, and R. de Jonge. 2013. “Evaluation of the HemoCue WBC DIFF System for Point-of-Care Counting of Total and Differential White Cells in Pediatric Samples.” Ned Tijdschr Klin Chem.

Lindberg, Stellan, Inger Jönsson, Magnus Nilsson, Elin Johnsson, and Tomas Jonasson-Bjäräng. 2014. “A Novel Technology for 5-Part Differentiation of Leukocytes Point-of-Care.” Point of Care 13 (2).

Willburn Medica, “HEMOCUE 123001 WHITE BLOOD CELL COUNTER & ACCESSORIES

(1) HemoCue, “HemoCue WBC instructions film“, YouTube, 2012.

Compliance with regulations

None

Evaluation methods

Waiting for response from manufacturer  

Other Information

None

Comments from the Community

6 Comments

  1. David Fulford says:

    The main material is polyethylene, which is cheap, but has a short lifetime. It is only the fittings that are of PVC. A 40 m3 system provides enough gas to run a small engine for a few hours a day to generate electrcity, as long as there is sufficient feed material, usually cattle dung. The performance figures seem reasonable.

  2. Arun Venkatesan says:

    Not available yet?

  3. E4C.COMMENTS says:

    Jeremy Schonhorn says:

    A few more references

    Hemocue References

    Casey, Janet R., and Michael E. Pichichero. 2009. “A Comparison of 2 White Blood Cell Count Devices to Aid Judicious Antibiotic Prescribing.” Clinical Pediatrics 48 (3): 291–94.

    Russcher, H., N. Van Deursen, and R. de Jonge. 2013. “Evaluation of the HemoCue WBC DIFF System for Point-of-Care Counting of Total and Differential White Cells in Pediatric Samples.” Ned Tijdschr Klin Chem. nvkc.nl. https://www.nvkc.nl/sites/d….

    Lindberg, Stellan, Inger Jönsson, Magnus Nilsson, Elin Johnsson, and Tomas Jonasson-Bjäräng. 2014. “A Novel Technology for 5-Part Differentiation of Leukocytes Point-of-Care.” Point of Care 13 (2). journals.lww.com: 27.

  4. E4C.COMMENTS says:

    Jeremy Schonhorn says:

    The Hemocue WBC Diff system is a vetted technology to determine white blood cell count (neutrophils, lymphocytes, monocytes, eosinophils and basophils). Although the device is powered with batteries, they are increasingly accessible in remote locations and should not be considered a limitation to usability and portability.

    The technology is accessible and ability to profile blood at the point of care from finger stick whole blood will enable physicians and health care providers to assess patient health (e.g. trauma, infection).

  5. Hernan Figueroa says:

    Two fields in the performance parameter table for this kind of products: “ICT technology platform” is not appropriate (Maximum current and Maximum power)
    The firmware that Angaza provides should be in terms of quality of service. Two suggestion would be additional cost to products, bandwidth requirement and training/technical support.

  6. Hernan Figueroa says:

    Checking the ICT only field, the performance parameters make more sense for Angaza and Lumeter: User coverage, service needed, etc.

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