PATH Disposable Syringe Jet Injector (DSJI)

Product Description

The PATH disposable-syringe jet injector (DSJI) is a sterile needle-free device that uses a single-dose syringe and a pressurized liquid stream rather than a needle to penetrate through the skin and deliver injections to the intradermal, subcutaneous, or intramuscular tissues. The PATH DSJI aims to reduce needle reuse and the associated disease spread due to shortages of sterile needles and trained lab workers. An estimated 23.5 million new HIV, hepatitis B, and hepatitis C infections occur every year through needle reuse and accidental needle stick injuries.

Distributors / Implementing Organizations

PATH partners with privately-held manufacturers such as PharmaJet that sell the product to medical dispensaries.

Manufacturing/Building Method

A pressurized liquid stream containing the vaccine/medicine directly enters the skin tissue without using a needle to pierce the skin. This direct injection delivers medicine and ensures that no contamination is observed. DSJIs require no change in vaccine formulation and can be filled from multi-dose and single-dose vials at the point of use.

Intellectural Property Type

Patent Protected

User Provision Model

This product is distributed by humanitarian organizations like WHO to health care professionals and centers.

Distributions to Date Status

PATH is conducting user assessments of device prototypes based on user feedback and has supported clinical research activities.

Delivery depths

The depth of delivery can be made to vary from intradermal (the 2-mm thick upper layer of the skin) all the way to intramuscular depths

Maximum injection volume (mL)

Unknown

Design Specifications

The process of delivering medicines and vaccines in primitive and culminates infections or contamination. However, newer technological advances like needle-free jet injection have the potential to improve safety by eliminating needles from the process of administering vaccines. Jet injectors create a fine stream of pressurized liquid that penetrates the skin, delivering doses of medications and vaccines while reducing hazardous waste. The potential benefits of jet injectors include more consistent delivery, reduced vaccine wastage, elimination of the need to transport large volumes of needles, and reduction of the risk of needle sticks and of the costs associated with sharp waste.

Technical Support

Provided by the manufacturer

Replacement Components

There are no replaceable components other than the vaccine/medicine vials.

Lifecycle

Unknown

Manufacturer Specified Performance Parameters

Usability, affordability of materials, and improved safety features

Vetted Performance Status

Testing performed by the manufacturer, however, no third-party testing has been completed.

Safety

No known safety hazards are related to this product.

Complementary Technical Systems

A reliable medical/health care is essential to use this product.

Academic Research and References

Weston, T. E. (1996). U.S. Patent No. 5,480,381. Washington, DC: U.S. Patent and Trademark Office.

Alchas, P. G., & Prais, A. W. (1994). U.S. Patent No. 5,334,144. Washington, DC: U.S. Patent and Trademark Office.

Singh, I., & Morris, A. P. (2011). Performance of transdermal therapeutic systems: Effects of biological factors. International journal of pharmaceutical investigation, 1(1), 4.

Compliance with regulations

The product is approved by WHO standards.

Other Information

Disposable-syringe jet injector technology has the potential to provide safer and more affordable vaccines to millions of people around the world as claimed by WHO.